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Radiotherapy Combined with Intratumoral Dendritic Cell Vaccination Enhances the Therapeutic Efficacy of Adoptive T-Cell Transfer
Treatment of C57BL/6 mice with cyclophosphamide (100 mg/kg) and fludarabine (200 mg/kg) induced non-myeloablative lymphodepletion without inhibiting D5 melanoma tumor growth. Utilizing this model, we found that induction of lymphopenia prior to adoptive transfer of ex vivo anti-CD3/CD28 activated an...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743975/ https://ncbi.nlm.nih.gov/pubmed/19483649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181a95165 |
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