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TGF-β1 Gene Silencing for Treating Liver Fibrosis

Small interfering RNA (siRNA) and short hairpin RNA (shRNA) targeting different regions of transforming growth factor β1 (TGF-β1) mRNA were designed and the silencing effect was determined after transfection into immortalized rat liver stellate cells (HSC-T6). There was not only significant decrease...

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Autori principali: Cheng, Kun, Yang, Ningning, Mahato, Ram I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743970/
https://ncbi.nlm.nih.gov/pubmed/19388665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp9000469
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