Mapping hypoxia-induced bioenergetic rearrangements and metabolic signaling by (18)O-assisted (31)P NMR and (1)H NMR spectroscopy

Brief hypoxia or ischemia perturbs energy metabolism inducing paradoxically a stress-tolerant state, yet metabolic signals that trigger cytoprotection remain poorly understood. To evaluate bioenergetic rearrangements, control and hypoxic hearts were analyzed with (18)O-assisted (31)P NMR and (1)H NM...

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Autori principali: Pucar, Darko, Dzeja, Petras P., Bast, Peter, Gumina, Richard J., Drahl, Carmen, Lim, Lynette, Juranic, Nenad, Macura, Slobodan, Terzic, Andre
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743901/
https://ncbi.nlm.nih.gov/pubmed/14977188
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