Silibinin prevents amyloid β peptide-induced memory impairment and oxidative stress in mice

BACKGROUND AND PURPOSE: Accumulated evidence suggests that oxidative stress is involved in amyloid β (Aβ)-induced cognitive dysfunction. Silibinin (silybin), a flavonoid derived from the herb milk thistle (Silybum marianum), has been shown to have antioxidative properties; however, it remains unclea...

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Bibliographic Details
Main Authors: Lu, P, Mamiya, T, Lu, LL, Mouri, A, Zou, LB, Nagai, T, Hiramatsu, M, Ikejima, T, Nabeshima, T
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743846/
https://ncbi.nlm.nih.gov/pubmed/19552690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00295.x
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