Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation

BACKGROUND: Rho iso-alpha acids (RIAA) from hops have been shown to have anti-inflammatory properties. To understand the mechanisms, we evaluated the effect of RIAA in cell signaling pathways and inflammatory markers using various in vitro models. We also investigated their therapeutic effect in mic...

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Detalhes bibliográficos
Main Authors: Konda, Veera Reddy, Desai, Anuradha, Darland, Gary, Bland, Jeffrey S, Tripp, Matthew L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743673/
https://ncbi.nlm.nih.gov/pubmed/19712471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-6-26
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