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Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
Tumour suppressor genes (TSGs) inhibiting normal cellular growth are frequently silenced epigenetically in cancer1. DNA methylation is commonly associated with TSG silencing1, yet mutations in the DNA methylation initiation and recognition machinery in carcinogenesis are unknown2. An intriguing poss...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743558/ https://ncbi.nlm.nih.gov/pubmed/18185590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06468 |
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