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Thrombin Inhibition By Argatroban Ameliorates Early Brain Injury And Improves Neurological Outcomes After Experimental Subarachnoid Hemorrhage In Rat
BACKGROUND AND PURPOSE: We investigated the role of thrombin in early brain injury after subarachnoid hemorrhage (SAH). METHODS: The standard intravascular perforation model was used to produce experimental SAH in Sprague Dawley rats. Low dose (0.3mg/hr) and high dose (0.3mg/hr) of argatroban, a dir...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743552/ https://ncbi.nlm.nih.gov/pubmed/19228846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.531699 |
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