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Population Pharmacokinetic/Pharmacodyanamic Mixture Models via Maximum a Posteriori Estimation
Pharmacokinetic/pharmacodynamic phenotypes are identified using nonlinear random effects models with finite mixture structures. A maximum a posteriori probability estimation approach is presented using an EM algorithm with importance sampling. Parameters for the conjugate prior densities can be base...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743512/ https://ncbi.nlm.nih.gov/pubmed/20161085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2009.04.017 |
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