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HOW A SINGLE-POINT MUTATION IN HORSERADISH PEROXIDASE MARKEDLY ENHANCES ENANTIOSELECTIVITY
The effect of all possible mutations at position 178 on the enantioselectivity of yeast surface-bound horseradish peroxidase (HRP) toward chiral phenols has been investigated. In contrast to their wild-type predecessor, most HRP mutants are enantioselective, with the Arg178Glu variant exhibiting the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743472/ https://ncbi.nlm.nih.gov/pubmed/19610634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja903482u |
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