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Proteomic profiling of K(ATP) channel-deficient hypertensive heart maps risk for maladaptive cardiomyopathic outcome

KCNJ11 null mutants, lacking Kir6.2 ATP-sensitive K(+) (K(ATP)) channels, exhibit a marked susceptibility towards hypertension (HTN)-induced heart failure. To gain insight into the molecular alterations induced by knockout of this metabolic sensor under hemodynamic stress, wild-type (WT) and Kir6.2...

詳細記述

保存先:
書誌詳細
主要な著者: Zlatkovic, Jelena, Arrell, D. Kent, Kane, Garvan C., Miki, Takashi, Seino, Susumu, Terzic, Andre
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743411/
https://ncbi.nlm.nih.gov/pubmed/19253285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800718
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