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Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells
Satellite cells in skeletal muscle are a heterogeneous population of stem cells and committed progenitors. We found that quiescent satellite stem cells expressed the Wnt-receptor Fzd7, and that its candidate ligand Wnt7a was upregulated during regeneration. Notably, Wnt7a markedly stimulated the sym...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743383/ https://ncbi.nlm.nih.gov/pubmed/19497282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.03.013 |
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