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Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

Satellite cells in skeletal muscle are a heterogeneous population of stem cells and committed progenitors. We found that quiescent satellite stem cells expressed the Wnt-receptor Fzd7, and that its candidate ligand Wnt7a was upregulated during regeneration. Notably, Wnt7a markedly stimulated the sym...

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Detaylı Bibliyografya
Asıl Yazarlar: Le Grand, Fabien, Jones, Andrew E., Seale, Vanessa, Scimè, Anthony, Rudnicki, Michael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743383/
https://ncbi.nlm.nih.gov/pubmed/19497282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.03.013
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