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Crosslinking Studies of Protein-Protein Interactions in Nonribosomal Peptide Biosynthesis

Selective protein-protein interactions between nonribosomal peptide synthetase (NRPS) proteins, governed by communication-mediating (COM) domains, are responsible for proper translocation of biosynthetic intermediates to produce the natural product. In this study, we developed a crosslinking assay,...

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Autors principals: Hur, Gene H., Meier, Jordan L., Baskin, Jeremy, Codelli, Julian A., Bertozzi, Carolyn R., Marahiel, Mohamed A., Burkart, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743379/
https://ncbi.nlm.nih.gov/pubmed/19345117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.02.009
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