Preoperative downstaging chemoradiation with concurrent irinotecan and capecitabine in MRI-defined locally advanced rectal cancer: a phase I trial (NWCOG-2)

BACKGROUND: The aim of this study was to investigate the safety of neoadjuvant chemoradiation using radiotherapy (RT) combined with concurrent capecitabine and irinotecan for locally advanced rectal cancer before surgery. METHODS: Forty-six patients were recruited and treated on the basis that MRI s...

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Main Authors: Gollins, S W, Myint, S, Susnerwala, S, Haylock, B, Wise, M, Topham, C, Samuel, L, Swindell, R, Morris, J, Mason, L, Levine, E
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2009
主題:
Clinical Study
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743353/
https://ncbi.nlm.nih.gov/pubmed/19690550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605258
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