Irinotecan+5-fluorouracil with concomitant pre-operative radiotherapy in locally advanced non-resectable rectal cancer: a phase I/II study

In the UK, 10% of patients diagnosed with rectal cancer have inoperable disease at presentation. This study ascertained whether the resectability rate of inoperable locally advanced rectal cancer was improved by administration of intravenous irinotecan, 5-fluorouracil (5-FU) and pelvic radiotherapy....

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Detalhes bibliográficos
Main Authors: Iles, S M, Gollins, S W, Susnerwala, S, Haylock, B, Myint, S, Biswas, A, Swindell, R, Levine, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359647/
https://ncbi.nlm.nih.gov/pubmed/18349840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604292
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