Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival

BACKGROUND: DNA aneuploidy reflects gross genomic changes. It can be measured by flow cytometry (FCM-DNA) or image cytometry (ICM-DNA). In gastric cancer, the prevalence of DNA aneuploidy has been reported to range from 27 to 100%, with conflicting associations with clinicopathological variables. Th...

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Detalhes bibliográficos
Main Authors: Belien, J A M, Buffart, T E, Gill, A J, Broeckaert, M A M, Quirke, P, Meijer, G A, Grabsch, H I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743350/
https://ncbi.nlm.nih.gov/pubmed/19738619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605266
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