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15-LOX-1 Transcription Suppression via the NuRD Complex in Colon Cancer Cells
15-Lipoxygenase-1 (15-LOX-1) is transcriptionally silenced in cancer cells, and its transcription reactivation (e.g., via histone deacetylase inhibitors [HDACIs]) restores apoptosis to cancer cells. However, the exact mechanism underlying 15-LOX-1 transcription reactivation in cancer cells is still...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743348/ https://ncbi.nlm.nih.gov/pubmed/19198625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.494 |
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