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15-LOX-1 Transcription Suppression via the NuRD Complex in Colon Cancer Cells

15-Lipoxygenase-1 (15-LOX-1) is transcriptionally silenced in cancer cells, and its transcription reactivation (e.g., via histone deacetylase inhibitors [HDACIs]) restores apoptosis to cancer cells. However, the exact mechanism underlying 15-LOX-1 transcription reactivation in cancer cells is still...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zuo, Xiangsheng, Morris, Jeffrey S., Broaddus, Russell, Shureiqi, Imad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743348/
https://ncbi.nlm.nih.gov/pubmed/19198625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.494
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