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An all-atom knowledge-based energy function for protein-DNA threading, docking decoy discrimination, and prediction of transcription-factor binding profiles
How to make an accurate representation of protein-DNA interactions by an energy function is a long-standing unsolved problem in structural biology. Here, we modified a statistical potential based on the distance-scaled, finite ideal-gas reference state (DFIRE) so that it is optimized for protein-DNA...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743280/ https://ncbi.nlm.nih.gov/pubmed/19274740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22384 |
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