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Asymmetric Amino Acid Activation by Class II Histidyl-tRNA Synthetase from Escherichia coli

Aminoacyl-tRNA synthetases (ARSs) join amino acids to their cognate tRNAs to initiate protein synthesis. Class II ARS possess a unique catalytic domain fold, possess active site signature sequences, and are dimers or tetramers. The dimeric class I enzymes, notably TyrRS, exhibit half-of-sites reacti...

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Detalhes bibliográficos
Main Authors: Guth, Ethan, Farris, Mindy, Bovee, Michael, Francklyn, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743188/
https://ncbi.nlm.nih.gov/pubmed/19487703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021311
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