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CXCR4 and MMP-1 are elevated in breast carcinoma-associated fibroblasts and in normal mammary fibroblasts exposed to factors secreted by breast cancer cells

The complex molecular communications that occur between neoplastic and stromal cells within the tumor microenvironment play an integral role in breast cancer pathogenesis. Carcinoma-associated fibroblasts (CAFs) produce tumor-enhancing factors and have been strongly implicated in breast cancer devel...

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Detalhes bibliográficos
Main Authors: Eck, SM, Côté, AL, Winkelman, WD, Brinckerhoff, CE
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743167/
https://ncbi.nlm.nih.gov/pubmed/19584257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0015
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