p53 promotes the fidelity of DNA end-joining activity by, in part, enhancing the expression of heterogeneous nuclear ribonucleoprotein G

Many studies have suggested the involvement of wild-type (wt) p53 in the repair of DNA double-strand breaks (DSBs) via DNA end-joining (EJ) process. To investigate this possibility, we compared the capacity and fidelity of DNA EJ in RKO cells containing wt p53 and RKO cells containing no p53 (RKO ce...

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Detalhes bibliográficos
Main Authors: Shin, Ki-Hyuk, Kim, Reuben H., Kang, Mo K., Kim, Roy, Kim, Steve, Lim, Philip K., Yochim, Ji Min, Baluda, Marcel A., Park, No-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743147/
https://ncbi.nlm.nih.gov/pubmed/17387044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.01.013
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