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MYC-induced myeloid leukemogenesis is accelerated by all six members of the anti-apoptotic BCL family

Signals that control the fine balance between cell death and cell survival are altered in cells during tumorigenesis. Understanding the mechanisms by which this balance is perturbed, leading to excessive cell survival, is important for designing effective therapies. Proteins belonging to the BCL fam...

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Autors principals: Beverly, Levi J., Varmus, Harold E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743088/
https://ncbi.nlm.nih.gov/pubmed/19137012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.466
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