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Global analysis of alternative splicing uncovers developmental regulation of nonsense-mediated decay in C. elegans
Alternative splicing coupled to nonsense-mediated decay (AS-NMD) is a mechanism for post-transcriptional regulation of gene expression. We analyzed the global effects of mutations in seven genes of the C. elegans NMD pathway on AS isoform ratios. We find that mutations in two NMD factors, smg-6 and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743056/ https://ncbi.nlm.nih.gov/pubmed/19617316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1711109 |
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