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Alternative Splicing and the Steady-State Ratios of mRNA Isoforms Generated by It Are under Strong Stabilizing Selection in Caenorhabditis elegans

Evolutionary studies indicate that a high proportion of alternative splicing (AS) events are species-specific; just 28% of minor-form alternatively spliced exons are conserved between mice and humans. We employed a splicing-sensitive microarray to study the evolution of allele-specific AS in nematod...

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Detalhes bibliográficos
Main Authors: Barberan-Soler, Sergio, Zahler, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727388/
https://ncbi.nlm.nih.gov/pubmed/18718918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn181
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