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Costimulatory molecule ICOS plays a critical role in the development of T(H)-17 and follicular T-helper cells by regulating c-Maf expression and IL-21 production
The inducible costimulatory molecule (ICOS) has been suggested to play an important role in the development of interleukin 17 (IL-17)-producing T helper cells (T(H)-17 cells) and of follicular helper cells (T(FH) cells), specialized helper T cells (CD4(+)CXCR5(+)ICOS(high)) required for antibody cla...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742982/ https://ncbi.nlm.nih.gov/pubmed/19098919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1690 |
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