B Cell Lymphoma (Bcl)-2 Protein Is the Major Determinant in bcl-2 Adenine-Uridine-rich Element Turnover Overcoming HuR Activity

In the 3′-untranslated region, the destabilizing adenine-uridine (AU)-rich elements (AREs) control the expression of several transcripts through interactions with ARE-binding proteins (AUBPs) and RNA degradation machinery. Although the fundamental role for AUBPs and associated factors in eliciting A...

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Autors principals: Ghisolfi, Laura, Calastretti, Angela, Franzi, Sara, Canti, Gianfranco, Donnini, Martino, Capaccioli, Sergio, Nicolin, Angelo, Bevilacqua, Annamaria
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
RNA: Processing and Catalysis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742860/
https://ncbi.nlm.nih.gov/pubmed/19520857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023721
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