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Farnesylation of Pex19p Is Required for Its Structural Integrity and Function in Peroxisome Biogenesis

The conserved CaaX box peroxin Pex19p is known to be modified by farnesylation. The possible involvement of this lipid modification in peroxisome biogenesis, the degree to which Pex19p is farnesylated, and its molecular function are unknown or controversial. We resolve these issues by first showing...

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Main Authors: Rucktäschel, Robert, Thoms, Sven, Sidorovitch, Vadim, Halbach, Andre, Pechlivanis, Markos, Volkmer, Rudolf, Alexandrov, Kirill, Kuhlmann, Jürgen, Rottensteiner, Hanspeter, Erdmann, Ralf
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742854/
https://ncbi.nlm.nih.gov/pubmed/19451657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016584
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