Combinatorial Transcription Factor Regulation of the Cyclic AMP-response Element on the Pgc-1α Promoter in White 3T3-L1 and Brown HIB-1B Preadipocytes

Cold stress in rodents increases the expression of UCP1 and PGC-1α in brown and white adipose tissue. We have previously reported that C/EBPβ specifically binds to the CRE on the proximal Pgc-1α promoter and increases forskolin-sensitive Pgc-1α and Ucp1 expression in white 3T3-L1 preadipocytes. Here...

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Bibliographic Details
Main Authors: Karamitri, Angeliki, Shore, Andrew M., Docherty, Kevin, Speakman, John R., Lomax, Michael A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Molecular Basis of Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742839/
https://ncbi.nlm.nih.gov/pubmed/19491401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021766
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