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Synergism between cAMP and PPARγ Signalling in the Initiation of UCP1 Gene Expression in HIB1B Brown Adipocytes

Expression of the brown adipocyte-specific gene, uncoupling protein 1 (UCP1), is increased by both PPARγ stimulation and cAMP activation through their ability to stimulate the expression of the PPAR coactivator PGC1α. In HIB1B brown preadipocytes, combination of the PPARγ agonist, rosiglitazone, and...

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Detalhes bibliográficos
Main Authors: Chen, H. Y., Liu, Q., Salter, A. M., Lomax, M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608182/
https://ncbi.nlm.nih.gov/pubmed/23554809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/476049
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