Caricamento...

Calmodulin Activation Limits the Rate of KCNQ2 K(+) Channel Exit from the Endoplasmic Reticulum

The potential regulation of protein trafficking by calmodulin (CaM) is a novel concept that remains to be substantiated. We proposed that KCNQ2 K(+) channel trafficking is regulated by CaM binding to the C-terminal A and B helices. Here we show that the L339R mutation in helix A, which is linked to...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Alaimo, Alessandro, Gómez-Posada, Juan Camilo, Aivar, Paloma, Etxeberría, Ainhoa, Rodriguez-Alfaro, Jose Angel, Areso, Pilar, Villarroel, Alvaro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742831/
https://ncbi.nlm.nih.gov/pubmed/19494108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019539
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !