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Thrombin Promotes Release of ATP from Lung Epithelial Cells through Coordinated Activation of Rho- and Ca(2+)-dependent Signaling Pathways

Extracellular ATP controls key aspects of lung function via activation of epithelial cell purinergic receptors, but how ATP is released from cells remains poorly understood. To identify mechanistic components upstream of ATP release, we examined the effect of selected G protein coupled-receptor acti...

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Autori principali: Seminario-Vidal, Lucia, Kreda, Silvia, Jones, Lisa, O'Neal, Wanda, Trejo, JoAnn, Boucher, Richard C., Lazarowski, Eduardo R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742828/
https://ncbi.nlm.nih.gov/pubmed/19439413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004762
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