Thrombin Promotes Release of ATP from Lung Epithelial Cells through Coordinated Activation of Rho- and Ca(2+)-dependent Signaling Pathways

Extracellular ATP controls key aspects of lung function via activation of epithelial cell purinergic receptors, but how ATP is released from cells remains poorly understood. To identify mechanistic components upstream of ATP release, we examined the effect of selected G protein coupled-receptor acti...

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Detalhes bibliográficos
Main Authors: Seminario-Vidal, Lucia, Kreda, Silvia, Jones, Lisa, O'Neal, Wanda, Trejo, JoAnn, Boucher, Richard C., Lazarowski, Eduardo R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742828/
https://ncbi.nlm.nih.gov/pubmed/19439413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004762
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