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Thrombin Promotes Release of ATP from Lung Epithelial Cells through Coordinated Activation of Rho- and Ca(2+)-dependent Signaling Pathways

Extracellular ATP controls key aspects of lung function via activation of epithelial cell purinergic receptors, but how ATP is released from cells remains poorly understood. To identify mechanistic components upstream of ATP release, we examined the effect of selected G protein coupled-receptor acti...

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Autors principals: Seminario-Vidal, Lucia, Kreda, Silvia, Jones, Lisa, O'Neal, Wanda, Trejo, JoAnn, Boucher, Richard C., Lazarowski, Eduardo R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742828/
https://ncbi.nlm.nih.gov/pubmed/19439413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004762
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