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Retinoids Induce Cytochrome P450 3A4 through RXR/VDR-mediated Pathway
A panel of retinoids and carotenoids was screened as potential inducers of CYP3A4 through the RXR/VDR-mediated signaling pathway. Transient transfection assays revealed that 3 out of 12 retinoids screened transactivated RXRα/VDR and induced CYP3A4 reporter activity. These three retinoids are the act...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742682/ https://ncbi.nlm.nih.gov/pubmed/18400206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.02.030 |
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