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Retinoids Induce Cytochrome P450 3A4 through RXR/VDR-mediated Pathway

A panel of retinoids and carotenoids was screened as potential inducers of CYP3A4 through the RXR/VDR-mediated signaling pathway. Transient transfection assays revealed that 3 out of 12 retinoids screened transactivated RXRα/VDR and induced CYP3A4 reporter activity. These three retinoids are the act...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Kun, Chen, Shiyong, Xie, Wen, Wan, Yu-Jui Yvonne
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742682/
https://ncbi.nlm.nih.gov/pubmed/18400206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.02.030
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