FREQUENCIES OF PERIPHERAL BLOOD MYELOID CELLS IN HEALTHY KENYAN CHILDREN WITH α+ THALASSEMIA AND THE SICKLE CELL TRAIT

The high frequencies of both α+ thalassemia and the sickle cell trait (hemoglobin AS [HbAS]) found in many tropical populations are thought to reflect selection pressure from Plasmodium falciparum malaria. For HbAS, but not for α+ thalassemia, protection appears to be mediated by the enhanced phagoc...

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Main Authors: URBAN, BRITTA C., SHAFI, MOHAMMED J., CORDERY, DAMIEN V., MACHARIA, ALEX, LOWE, BRETT, MARSH, KEVIN, WILLIAMS, THOMAS N.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742660/
https://ncbi.nlm.nih.gov/pubmed/16606987
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