Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk

BACKGROUND: Inherited risk of pancreatic cancer has been associated with mutations in several genes, including BRCA2, CDKN2A (p16), PRSS1, and PALB2. We hypothesized that common variants in these genes, single nucleotide polymorphisms (SNPs), may also influence risk for pancreatic cancer development...

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Autori principali: McWilliams, Robert R., Bamlet, William R., de Andrade, Mariza, Rider, David N., Couch, Fergus J., Cunningham, Julie M., Matsumoto, Martha E., Rabé, Kari G., Hammer, Traci J., Petersen, Gloria M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742574/
https://ncbi.nlm.nih.gov/pubmed/19690177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0605
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