Association of Mitotic Regulation Pathway Polymorphisms with Pancreatic Cancer Risk and Outcome

BACKGROUND: Mitosis is a highly regulated process that serves to ensure the fidelity of cell division. Disruption of mitotic regulators leading to aneuploidy and polyploidy is commonly observed in cancer cells. Single nucleotide polymorphisms (SNPs) in regulators of mitosis may promote chromosome mi...

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Main Authors: Couch, Fergus J., Wang, Xianshu, Bamlet, William R., de Andrade, Mariza, Petersen, Gloria M., McWilliams, Robert R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805468/
https://ncbi.nlm.nih.gov/pubmed/20056645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0629
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