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Strand-Invasion of Extended, Mixed-Sequence B-DNA by γPNAs
In this Communication we show that peptide nucleic acids (PNAs), 15 to 20nt in length, when preorganized into a right-handed helix, can invade mixed-sequence double helical B-form DNA (B-DNA). Strand-invasion occurs in a highly sequence-specific manner through direct Watson-Crick base-pairing. Unlik...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742410/ https://ncbi.nlm.nih.gov/pubmed/19663424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja900228j |
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