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Loss of dendrite stabilization by the Abl-related gene (Arg) kinase regulates behavioral flexibility and sensitivity to cocaine

Adolescence is characterized by increased vulnerability to developing neuropsychiatric disorders and involves a period of prefrontal cortical dendritic refinement and synaptic pruning that culminates in cytoskeletal stabilization in adulthood. The Abl-related gene (Arg) acts through p190RhoGAP to in...

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Détails bibliographiques
Auteurs principaux: Gourley, Shannon L., Koleske, Anthony J., Taylor, Jane R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742404/
https://ncbi.nlm.nih.gov/pubmed/19805386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902286106
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