Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients

The opportunistic pathogen Pseudomonas aeruginosa undergoes genetic change during chronic airway infection of cystic fibrosis (CF) patients. One common change is a mutation inactivating lasR, which encodes a transcriptional regulator that responds to a homoserine lactone signal to activate expressio...

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Autors principals: D’Argenio, David A., Wu, Manhong, Hoffman, Lucas R., Kulasekara, Hemantha D., Déziel, Eric, Smith, Eric E., Nguyen, Hai, Ernst, Robert K., Larson Freeman, Theodore J., Spencer, David H., Brittnacher, Mitchell, Hayden, Hillary S., Selgrade, Sara, Klausen, Mikkel, Goodlett, David R., Burns, Jane L., Ramsey, Bonnie W., Miller, Samuel I.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742308/
https://ncbi.nlm.nih.gov/pubmed/17493132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05678.x
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