Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels

Exchange proteins directly activated by cyclic AMP (Epacs or cAMP-GEF) represent a family of novel cAMP-binding effector proteins. The identification of Epacs and the recent development of pharmacological tools that discriminate between cAMP-mediated pathways have revealed previously unrecognized ro...

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Bibliografiska uppgifter
Huvudupphovsmän: Purves, Gregor I, Kamishima, Tomoko, Davies, Lowri M, Quayle, John M, Dart, Caroline
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2009
Ämnen:
Cardiovascular
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742287/
https://ncbi.nlm.nih.gov/pubmed/19491242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.173534
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