A single nucleotide polymorphism in osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli is associated with an increased risk of non-secretory bacterial diarrhea in US travelers to Mexico

BACKGROUND & AIMS: Osteoprotegerin (OPG), an immunoregulatory member of the TNF receptor superfamily, is expressed in inflamed intestinal mucosa. We investigated whether OPG is produced by intestinal epithelial cells and tested the hypothesis that single nucleotide polymorphisms (SNPs) in the os...

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Main Authors: Mohamed, Jamal A., DuPont, Herbert L., Jiang, Zhi-Dong, Flores, Jose, Carlin, Lily G., Belkind-Gerson, Jaime, Martinez-Sandoval, Francisco J., Guo, Dongchuan, White, Clinton A., Okhuysen, Pablo C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742228/
https://ncbi.nlm.nih.gov/pubmed/19128145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/596319
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