A single nucleotide polymorphism in osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli is associated with an increased risk of non-secretory bacterial diarrhea in US travelers to Mexico

BACKGROUND & AIMS: Osteoprotegerin (OPG), an immunoregulatory member of the TNF receptor superfamily, is expressed in inflamed intestinal mucosa. We investigated whether OPG is produced by intestinal epithelial cells and tested the hypothesis that single nucleotide polymorphisms (SNPs) in the os...

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Detalhes bibliográficos
Main Authors: Mohamed, Jamal A., DuPont, Herbert L., Jiang, Zhi-Dong, Flores, Jose, Carlin, Lily G., Belkind-Gerson, Jaime, Martinez-Sandoval, Francisco J., Guo, Dongchuan, White, Clinton A., Okhuysen, Pablo C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742228/
https://ncbi.nlm.nih.gov/pubmed/19128145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/596319
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