A single nucleotide polymorphism in osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli is associated with an increased risk of non-secretory bacterial diarrhea in US travelers to Mexico

BACKGROUND & AIMS: Osteoprotegerin (OPG), an immunoregulatory member of the TNF receptor superfamily, is expressed in inflamed intestinal mucosa. We investigated whether OPG is produced by intestinal epithelial cells and tested the hypothesis that single nucleotide polymorphisms (SNPs) in the os...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mohamed, Jamal A., DuPont, Herbert L., Jiang, Zhi-Dong, Flores, Jose, Carlin, Lily G., Belkind-Gerson, Jaime, Martinez-Sandoval, Francisco J., Guo, Dongchuan, White, Clinton A., Okhuysen, Pablo C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2009
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742228/
https://ncbi.nlm.nih.gov/pubmed/19128145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/596319
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