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NOVEL MICROTUBULE POLYMERIZATION INHIBITOR WITH POTENT ANTI-PROLIFERATIVE AND ANTI-TUMOR ACTIVITY

Microtubule stabilizing and destabilizing agents are commonly used as anti-cancer agents. Although highly effective, success with these agents has been limited due to their relative insolubility, cumbersome synthesis/purification, toxic side effects, and development of multidrug resistance. Hence th...

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Detalhes bibliográficos
Main Authors: Arora, Sonia, Wang, Xin I., Keenan, Susan M., Andaya, Christina, Zhang, Qiang, Peng, Youyi, Welsh, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742177/
https://ncbi.nlm.nih.gov/pubmed/19223556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0877
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