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Inhibition of Fatty Acid Synthase by Luteolin Post-Transcriptionally Downregulates c-Met Expression Independent of Proteosomal/Lysosomal Degradation

The HGF/c-Met signaling pathway is involved in the progression of a number of cancers and associated with increased tumor invasion and metastatic potential. We previously determined that the polyphenol epigallocatechin-3-gallate (EGCG) inhibited HGF-induced c-Met phosphorylation in a variety of tumo...

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Detalhes bibliográficos
Main Authors: Coleman, David T., Bigelow, Rebecca, Cardelli, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741738/
https://ncbi.nlm.nih.gov/pubmed/19139131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0722
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