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Peripheral Neuropathy in Rats Exposed to Dichloroacetate
The use of dichloroacetate (DCA) for treating patients with mitochondrial diseases is limited by the induction of peripheral neuropathy. The mechanisms of DCA-induced neuropathy are not known. Oral DCA treatment (50–500 mg/kg/day for up to 16 weeks) induced tactile allodynia in both juvenile and adu...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741559/ https://ncbi.nlm.nih.gov/pubmed/19680144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181b40217 |
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