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Inhibition of AP-1 by Sulforaphane Involves Interaction with Cysteine in the cFos DNA-Binding Domain; Implications for Chemoprevention of UVB-Induced Skin Cancer

Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables which has been linked to decreased risk of certain cancers. Although the role of SFN in the induction of the transcription factor Nrf2 has been studied extensively, there is also evidence that inhibition of the transcription...

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Hlavní autoři: Dickinson, Sally E., Melton, Tania F., Olson, Erik R., Zhang, Jian, Saboda, Kathylynn, Bowden, G. Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741483/
https://ncbi.nlm.nih.gov/pubmed/19671797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0770
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