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Dynamic Pax6 expression during the neurogenic cell cycle influences proliferation and cell fate choices of retinal progenitors

BACKGROUND: The paired homeobox protein Pax6 is essential for proliferation and pluripotency of retinal progenitors. However, temporal changes in Pax6 protein expression associated with the generation of various retinal neurons have not been characterized with regard to the cell cycle. Here, we exam...

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Autors principals: Hsieh, Yi-Wen, Yang, Xian-Jie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741438/
https://ncbi.nlm.nih.gov/pubmed/19686589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-4-32
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