Peptidyl-Prolyl Isomerase Pin1 Markedly Enhances the Oncogenic Activity of the Rel Proteins in the NF-κB family

The peptidyl-prolyl isomerase Pin1 is frequently upregulated in human cancers in which Rel/NF-κB is constitutively activated but its role in these cancers remains to be determined, and evidence is still lacking to show that Pin1 contributes to cell transformation by Rel/NF-κB. Rel/NF-κB’s transcript...

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Bibliographic Details
Main Authors: Fan, Gaofeng, Fan, Yongjun, Gupta, Nupur, Matsuura, Isao, Liu, Fang, Zhou, Xiao Zhen, Lu, Kun Ping, Gélinas, Céline
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741415/
https://ncbi.nlm.nih.gov/pubmed/19458071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4117
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