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Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women

Enzymes encoded by the glutathione S-tranferase mu 1 (GSTM1) and pi 1 (GSTP1) genes, which are expressed in breast tissue, catalyze the detoxification of endogenous and exogenous electrophiles. Reduced enzyme activity, due to carriage of the GSTM1 deletion or the GSTP1 Ile105Val Val allele, may ther...

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Detalhes bibliográficos
Main Authors: Sakoda, Lori C., Blackston, Christie R., Xue, Kan, Doherty, Jennifer A., Ray, Roberta M., Lin, Ming Gang, Stalsberg, Helge, Gao, Dao Li, Feng, Ziding, Thomas, David B., Chen, Chu
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741390/
https://ncbi.nlm.nih.gov/pubmed/17624589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-007-9633-5
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