Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women

Enzymes encoded by the glutathione S-tranferase mu 1 (GSTM1) and pi 1 (GSTP1) genes, which are expressed in breast tissue, catalyze the detoxification of endogenous and exogenous electrophiles. Reduced enzyme activity, due to carriage of the GSTM1 deletion or the GSTP1 Ile105Val Val allele, may ther...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sakoda, Lori C., Blackston, Christie R., Xue, Kan, Doherty, Jennifer A., Ray, Roberta M., Lin, Ming Gang, Stalsberg, Helge, Gao, Dao Li, Feng, Ziding, Thomas, David B., Chen, Chu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741390/
https://ncbi.nlm.nih.gov/pubmed/17624589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-007-9633-5
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