Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women

Enzymes encoded by the glutathione S-tranferase mu 1 (GSTM1) and pi 1 (GSTP1) genes, which are expressed in breast tissue, catalyze the detoxification of endogenous and exogenous electrophiles. Reduced enzyme activity, due to carriage of the GSTM1 deletion or the GSTP1 Ile105Val Val allele, may ther...

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Détails bibliographiques
Auteurs principaux: Sakoda, Lori C., Blackston, Christie R., Xue, Kan, Doherty, Jennifer A., Ray, Roberta M., Lin, Ming Gang, Stalsberg, Helge, Gao, Dao Li, Feng, Ziding, Thomas, David B., Chen, Chu
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741390/
https://ncbi.nlm.nih.gov/pubmed/17624589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-007-9633-5
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